BIOMO301-23B (HAM)

Advanced Biochemistry

15 Points

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The University of Waikato
Academic Divisions
Division of Health Engineering Computing & Science
School of Science
Biomedical, Molecular and Cellular Biology

Staff

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Convenor(s)

Joanna Hicks

Joanna Hicks
9399
CD.2.02
See Moodle
joanna.hicks@waikato.ac.nz

Lecturer(s)

Adele Williamson

Adele Williamson
0
CD.2.03
See Moodle
adele.williamson@waikato.ac.nz

Vic Arcus

Vic Arcus
4679
C.2.11
See Moodle
vic.arcus@waikato.ac.nz

Administrator(s)

: klaus.reiter@waikato.ac.nz

Placement/WIL Coordinator(s)

Tutor(s)

Student Representative(s)

Lab Technician(s)

Librarian(s)

: anne.ferrier-watson@waikato.ac.nz

You can contact staff by:

  • Calling +64 7 838 4466 select option 1, then enter the extension.
  • Extensions starting with 4, 5, 9 or 3 can also be direct dialled:
    • For extensions starting with 4: dial +64 7 838 extension.
    • For extensions starting with 5: dial +64 7 858 extension.
    • For extensions starting with 9: dial +64 7 837 extension.
    • For extensions starting with 3: dial +64 7 2620 + the last 3 digits of the extension e.g. 3123 = +64 7 262 0123.
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What this paper is about

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This paper builds on the principles of biochemistry introduced in BIOMO201 to examine molecular mechanisms underlying cellular communication and trafficking of proteins between organelles, cellular stress responses, cell death, and the degradation of biomolecules. Students will also examine the molecular basis of human diseases such as Diabetes and how protein structures are determined, the process of nucleotide metabolism and transcription and features of molecular motors (such as the ATP synthase). Students will also be required to critically evaluate and make oral presentations from primary research findings in biochemistry and molecular cell biology as part of the directed study section of this paper.
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How this paper will be taught

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This paper will be taught using lectures, workshops and practical laboratory sessions.
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Required Readings

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Text book: Appling, Anthony-Cahill & Mathews, Biochemistry: Concepts & Connections, 2018 2nd edition, Pearson Education (or Garnett & Grisham, Biochemistry, 6th edition can be used in 2022).

Lab and Lecture powerpoints: A copy of the lab manual can be picked up from the Waikato Print (Gravitas) (prior to the start of the labs). All lecture powerpoints will be on Moodle.

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Learning Outcomes

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Students who successfully complete the course should be able to:

  • Analyse molecular assemblies and their various functions
    Linked to the following assessments:
  • Describe key cellular processes including DNA replication, metabolism and protein trafficking
    Linked to the following assessments:
  • Evaluate biochemical techniques and their applications
    Linked to the following assessments:
  • Evaluate how molecular motors transform chemical energy into mechanical work
    Linked to the following assessments:
  • Illustrate how DNA repair enzymes work and their use in biotechnology applications
    Linked to the following assessments:
  • Investigate proteins using a variety of laboratory techniques
    Linked to the following assessments:
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Assessments

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How you will be assessed

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Internal:external assessment ratio 100:0 (no final exam)

Assessment consists of the following:
Workshop assessment activities -9 in person workshops over the semester (20%)

Test 1 (15%)

Test 2 (15%)

Test 3 (15%)

Practical Sessions (Lab Book) (15%)

Lab report (mini-research report of the experiments performed over the practical sessions) (20%)

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The internal assessment/exam ratio (as stated in the University Calendar) is 100:0. There is no final exam. The final exam makes up 0% of the overall mark.

The internal assessment/exam ratio (as stated in the University Calendar) is 100:0 or 0:0, whichever is more favourable for the student. The final exam makes up either 0% or 0% of the overall mark.

Component DescriptionDue Date TimePercentage of overall markSubmission MethodCompulsory
1. Workshop Assessments
20
  • Hand-in: In Workshop
  • Online: Submit through Moodle
2. Test 1
11 Aug 2023
12:00 PM
15
  • Hand-in: In Lecture
3. Test 2
22 Sep 2023
12:00 PM
15
  • Hand-in: In Lecture
4. Test 3
13 Oct 2023
12:00 PM
15
  • Hand-in: In Lecture
5. Practical Sessions (Lab Book)
15
  • Hand-in: In Lab
6. Mini-research Report (Lab Report)
20 Oct 2023
5:00 PM
20
  • Online: Submit through Moodle
Assessment Total:     100    
Failing to complete a compulsory assessment component of a paper will result in an IC grade
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